Is D53.1 a billable ICD-10-CM code?

Yes. D53.1 is a billable, specific ICD-10-CM code and is valid for submission on a claim.

Where does D53.1 sit in the tabular list?

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Nutritional anemias (D50-D53).

What cannot be coded together with D53.1?

D53.1 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.

D53.1

D53.1 — Other megaloblastic anemias, not elsewhere classified

Billable / specific codeICD-10-CM

D53.1 is a billable, specific ICD-10-CM code for other megaloblastic anemias, not elsewhere classified. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

Di Guglielmo's disease (C94.0)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Megaloblastic anemia NOS

Risk adjustment

D53.1 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

D53.1 is named in 6 Medicare coverage policies — 6 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

A56416Billing and Coding: Assays for Vitamins and Metabolic Function
A56464Billing and Coding: Flow Cytometry
A56675Billing and Coding: Homocysteine Level, Serum
A57188Billing and Coding: Routine Foot Care

How D53.1 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D53.1.

Megalocytic anemia
Anemia›achrestic
Anemia›dimorphic
Anemia›diphasic
Anemia›megaloblastic
Anemia›megalocytic
Anemia›deficiency›combined B12 and folate
Anemia›megaloblastic›combined B12 and folate deficiency
Anemia›megaloblastic›refractory
Anemia›megaloblastic›specified type NEC
Anemia›refractory›megaloblastic

Related codes at this level

Codes that share D53. If D53.1 is not quite right, the correct code is usually one of these.

Questions about D53.1

Is D53.1 a billable ICD-10-CM code?: Yes. D53.1 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D53.1 sit in the tabular list?: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Nutritional anemias (D50-D53).
What cannot be coded together with D53.1?: D53.1 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.