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D72.0

D72.0Genetic anomalies of leukocytes

Billable / specific codeICD-10-CM

D72.0 is a billable, specific ICD-10-CM code for genetic anomalies of leukocytes. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • Chédiak (-Steinbrinck)-Higashi syndrome (E70.330)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Alder (granulation) (granulocyte) anomaly
  • Alder syndrome
  • Hereditary leukocytic hypersegmentation
  • Hereditary leukocytic hyposegmentation
  • Hereditary leukomelanopathy
  • May-Hegglin (granulation) (granulocyte) anomaly
  • May-Hegglin syndrome
  • Pelger-Huët (granulation) (granulocyte) anomaly
  • Pelger-Huët syndrome

Risk adjustment

D72.0 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 115 Specified Immunodeficiencies and White Blood Cell Disorders0.565 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

D72.0 is named in 3 Medicare coverage policies 3 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A57689Billing and Coding: Lab: Flow Cytometry

How D72.0 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D72.0.

  • Alder(-Reilly) anomaly or syndrome (leukocyte granulation)
  • Dohle body panmyelopathic syndrome
  • Hegglin's anomaly or syndrome
  • Hypersegmentation, leukocytic, hereditary
  • Hyposegmentation, leukocytic, hereditary
  • Jordan's anomaly or syndrome
  • Leukomelanopathy, hereditary
  • May anomaly or syndrome(-Hegglin)
  • Neutrophilia, hereditary giant
  • Pelger-Huët anomaly or syndrome
  • Anomaly, anomalousAlder(-Reilly) (leukocyte granulation)
  • Anomaly, anomalousgranulation or granulocyte, genetic(constitutional) (leukocyte)

Related codes at this level

Codes that share D72. If D72.0 is not quite right, the correct code is usually one of these.

Questions about D72.0

Is D72.0 a billable ICD-10-CM code?
Yes. D72.0 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D72.0 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Other disorders of blood and blood-forming organs (D70-D77).
What cannot be coded together with D72.0?
D72.0 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.