MCMCB Pro
K21

K21Gastro-esophageal reflux disease

Non-billable headerICD-10-CM

K21 is a non-billable header ICD-10-CM code for gastro-esophageal reflux disease. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • newborn esophageal reflux (P78.83)

Other codes that can never be billed with K21

These codes carry an Excludes1 note pointing at K21. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading K21 alone.

Risk adjustment

K21 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead K21

2 child codes. Green means billable.

Questions about K21

Is K21 a billable ICD-10-CM code?
No. K21 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does K21 sit in the tabular list?
Diseases of the digestive system (K00-K95), in the block Diseases of esophagus, stomach and duodenum (K20-K31).
What cannot be coded together with K21?
K21 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.