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L51.2

L51.2Toxic epidermal necrolysis [Lyell]

Billable / specific codeICD-10-CM

L51.2 is a billable, specific ICD-10-CM code for toxic epidermal necrolysis [lyell]. It is valid for submission on a claim.

Other codes that can never be billed with L51.2

These codes carry an Excludes1 note pointing at L51.2. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading L51.2 alone.

  • L00Staphylococcal scalded skin syndrome

Risk adjustment

L51.2 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

L51.2 is named in 7 Medicare coverage policies 7 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A56786Billing and Coding: Immune Globulin
  • A57554Billing and Coding: Immune Globulins
  • A57778Billing and Coding: Immune Globulin
  • A59101Billing and Coding: Off-label Use of Rituximab and Rituximab Biosimilars

How L51.2 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to L51.2.

  • Lyell's syndrome
  • Necrolysis, toxic epidermal
  • Epidermolysisnecroticans combustiformis
  • Lyell's syndromedue to drug

Related codes at this level

Codes that share L51. If L51.2 is not quite right, the correct code is usually one of these.

Questions about L51.2

Is L51.2 a billable ICD-10-CM code?
Yes. L51.2 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does L51.2 sit in the tabular list?
Diseases of the skin and subcutaneous tissue (L00-L99), in the block Urticaria and erythema (L49-L54).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.