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E25

E25Adrenogenital disorders

Non-billable headerICD-10-CM

E25 is a non-billable header ICD-10-CM code for adrenogenital disorders. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • indeterminate sex and pseudohermaphroditism (Q56)
  • chromosomal abnormalities (Q90-Q99)

Includes

Conditions this code covers.

  • adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
  • Female adrenal pseudohermaphroditism
  • Female heterosexual precocious pseudopuberty
  • Male isosexual precocious pseudopuberty
  • Male macrogenitosomia praecox
  • Male sexual precocity with adrenal hyperplasia
  • Male virilization (female)

Other codes that can never be billed with E25

These codes carry an Excludes1 note pointing at E25. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E25 alone.

  • Q56Indeterminate sex and pseudohermaphroditism
  • Q89.1Congenital malformations of adrenal gland
  • E24Cushing's syndrome
  • E30.1Precocious puberty

Risk adjustment

E25 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead E25

3 child codes. Green means billable.

Questions about E25

Is E25 a billable ICD-10-CM code?
No. E25 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does E25 sit in the tabular list?
Endocrine, nutritional and metabolic diseases (E00-E89), in the block Disorders of other endocrine glands (E20-E35).
What cannot be coded together with E25?
E25 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.