MCMCB Pro
K21.00

K21.00Gastro-esophageal reflux disease with esophagitis, without bleeding

Billable / specific codeICD-10-CM

K21.00 is a billable, specific ICD-10-CM code for gastro-esophageal reflux disease with esophagitis, without bleeding. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Reflux esophagitis

Risk adjustment

K21.00 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

K21.00 is named in 21 Medicare coverage policies 17 listing it as supporting medical necessity, and 4 listing it as NOT covered. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A59015Billing and Coding: MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasianot covered
  • A59032Billing and Coding: MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasianot covered
  • A59051Billing and Coding: MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasianot covered
  • A59121Billing and Coding: MolDX: Molecular Testing for Detection of Upper Gastrointestinal Metaplasia, Dysplasia, and Neoplasianot covered

How K21.00 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to K21.00.

  • Esophagitisdue to gastrointestinal reflux disease(without bleeding)
  • Esophagitisreflux
  • Disease, diseasedgastroesophageal refluxwith esophagitis(without bleeding)
  • Refluxesophagealwith esophagitis(without bleeding)
  • Refluxgastroesophagealwith esophagitis(without bleeding)
  • Allergy, allergicmilk proteingastroesophageal refluxwith esophagitis(without bleeding)
  • Ulcer, ulcerated, ulcerating, ulceration, ulcerativeesophagusdue togastrointestinal reflux disease(without bleeding)

Related codes at this level

Codes that share K21.0. If K21.00 is not quite right, the correct code is usually one of these.

Questions about K21.00

Is K21.00 a billable ICD-10-CM code?
Yes. K21.00 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does K21.00 sit in the tabular list?
Diseases of the digestive system (K00-K95), in the block Diseases of esophagus, stomach and duodenum (K20-K31).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.