C9161 — Injection, aflibercept hd, 1 mg
C9161 is a HCPCS Level II code for injection, aflibercept hd, 1 mg. It belongs to the Outpatient Prospective Payment System section. It was terminated on March 31, 2024 and is not valid on new claims.
This code has been terminated
CMS terminated C9161 on March 31, 2024. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
The CMS record for C9161
- Long descriptor
- Injection, aflibercept hd, 1 mg
- Short descriptor
- Inj, aflibercept hd, 1 mg
- Added
- January 1, 2024
- Terminated
- March 31, 2024
- BETOS
- O1E
- Pricing indicator
- 53 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Statute.
Codes adjacent to C9161
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If C9161 is not quite right, the correct code is very often within a few positions of it.
- C9153Injection, amisulpride, 1 mgterminated
- C9154Injection, buprenorphine extended-release (brixadi), 1 mgterminated
- C9155Injection, epcoritamab-bysp, 0.16 mgterminated
- C9156Flotufolastat f 18, diagnostic, 1 millicurieterminated
- C9157Injection, tofersen, 1 mgterminated
- C9158Injection, risperidone, (uzedy), 1 mgterminated
- C9159Injection, prothrombin complex concentrate (human), balfaxar, per i.u. of factor ix activityterminated
- C9160Injection, daxibotulinumtoxina-lanm, 1 unitterminated
- C9162Injection, avacincaptad pegol, 0.1 mgterminated
- C9163Injection, talquetamab-tgvs, 0.25 mgterminated
- C9164Cantharidin for topical administration, 0.7%, single unit dose applicator (3.2 mg)terminated
- C9165Injection, elranatamab-bcmm, 1 mgterminated
- C9166Injection, secukinumab, intravenous, 1 mgterminated
- C9167Injection, adamts13, recombinant-krhn, 10 iuterminated
- C9168Injection, mirikizumab-mrkz, 1 mgterminated
- C9169Injection, nogapendekin alfa inbakicept-pmln, for intravesical use, 1 microgramterminated
Questions about C9161
What is HCPCS code C9161?
C9161 is a HCPCS Level II code for injection, aflibercept hd, 1 mg. It sits in the Outpatient Prospective Payment System section.
Does Medicare cover C9161?
The CMS HCPCS file marks C9161 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
Is C9161 still valid?
No. C9161 was terminated on March 31, 2024 and should not be used on new claims.