G2121 — Depression, anxiety, apathy, and psychosis assessed
G2121 is a HCPCS Level II code for depression, anxiety, apathy, and psychosis assessed. It belongs to the Procedures and Professional Services (Temporary) section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusM
Measurement code. Used for reporting purposes only; never paid.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for G2121
- Long descriptor
- Depression, anxiety, apathy, and psychosis assessed
- Short descriptor
- Psy dep anx ap and icd asse
- Added
- January 1, 2020
- BETOS
- Z2
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to G2121
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If G2121 is not quite right, the correct code is very often within a few positions of it.
- G2113Patient receiving >5 mg daily prednisone (or equivalent) for longer than 6 months, and improvement or no change in disease activity
- G2114Patients 66-80 years of age with at least one claim/encounter for frailty during the measurement period and a dispensed medication for dementia during the measurement period or the year prior to the measurement periodterminated
- G2115Patients 66 - 80 years of age with at least one claim/encounter for frailty during the measurement period and a dispensed medication for dementia during the measurement period or the year prior to the measurement period
- G2116Patients 66 - 80 years of age with at least one claim/encounter for frailty during the measurement period and an advanced illness diagnosis during the measurement period or the year prior to the measurement period
- G2117Patients 66-80 years of age with at least one claim/encounter for frailty during the measurement period and either one acute inpatient encounter with a diagnosis of advanced illness or two outpatient, observation, ed or nonacute inpatient encounters on different dates of service with an advanced illness diagnosis during the measurement period or the year prior to the measurement periodterminated
- G2118Patients 81 years of age and older with at least one claim/encounter for frailty during the measurement period
- G2119Within the past 2 years, calcium and/or vitamin d optimization has been ordered or performedterminated
- G2120Within the past 2 years, calcium and/or vitamin d optimization has not been ordered or performedterminated
- G2122Depression, anxiety, apathy, and psychosis not assessed
- G2123Patients 66-80 years of age and had at least one claim/encounter for frailty during the measurement period and either one acute inpatient encounter with a diagnosis of advanced illness or two outpatient, observation, ed or nonacute inpatient encounters on different dates of service with an advanced illness diagnosis during the measurement period or the year prior to the measurement periodterminated
- G2124Patients 66-80 years of age and had at least one claim/encounter for frailty during the measurement period and a dispensed dementia medicationterminated
- G2125Patients 81 years of age and older with at least one claim/encounter for frailty during the six months prior to the measurement period through december 31 of the measurement period
- G2126Patients 66-80 years of age with at least one claim/encounter for frailty during the measurement period and an advanced illness diagnosis during the measurement period or the year prior to the measurement period
- G2127Patients 66-80 years of age with at least one claim/encounter for frailty during the measurement period and a dispensed medication for dementia during the measurement period or the year prior to the measurement period
- G2128Documentation of medical reason(s) for not on a daily aspirin or other antiplatelet (e.g. history of gastrointestinal bleed, intra-cranial bleed, blood disorders, idiopathic thrombocytopenic purpura (itp), gastric bypass or documentation of active anticoagulant use during the measurement period)
- G2129Procedure-related bp's not taken during an outpatient visit. examples include same day surgery, ambulatory service center, g.i. lab, dialysis, infusion center, chemotherapy
Questions about G2121
What is HCPCS code G2121?
G2121 is a HCPCS Level II code for depression, anxiety, apathy, and psychosis assessed. It sits in the Procedures and Professional Services (Temporary) section.
Does Medicare cover G2121?
The CMS HCPCS file marks G2121 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is G2121 paid under the physician fee schedule?
G2121 carries PFS status code M. Measurement code. Used for reporting purposes only; never paid.