J0215 — Injection, alefacept, 0.5 mg
J0215 is a HCPCS Level II code for injection, alefacept, 0.5 mg. It belongs to the Drugs Administered Other Than Oral Method section. It was terminated on December 31, 2025 and is not valid on new claims.
This code has been terminated
CMS terminated J0215 on December 31, 2025. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
The CMS record for J0215
- Long descriptor
- Injection, alefacept, 0.5 mg
- Short descriptor
- Alefacept
- Added
- January 1, 2004
- Terminated
- December 31, 2025
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J0215
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J0215 is not quite right, the correct code is very often within a few positions of it.
- J0202Injection, alemtuzumab, 1 mg
- J0205Injection, alglucerase, per 10 unitsterminated
- J0206Injection, allopurinol sodium, 1 mg
- J0207Injection, amifostine, 500 mg
- J0208Injection, sodium thiosulfate (pedmark), 100 mg
- J0209Injection, sodium thiosulfate (hope), 100 mg
- J0210Injection, methyldopate hcl, up to 250 mg
- J0211Injection, sodium nitrite 3 mg and sodium thiosulfate 125 mg (nithiodote)
- J0216Injection, alfentanil hydrochloride, 500 micrograms
- J0217Injection, velmanase alfa-tycv, 1 mg
- J0218Injection, olipudase alfa-rpcp, 1 mg
- J0219Injection, avalglucosidase alfa-ngpt, 4 mg
- J0220Injection, alglucosidase alfa, 10 mg, not otherwise specified
- J0221Injection, alglucosidase alfa, (lumizyme), 10 mg
- J0222Injection, patisiran, 0.1 mg
- J0223Injection, givosiran, 0.5 mg
Questions about J0215
What is HCPCS code J0215?
J0215 is a HCPCS Level II code for injection, alefacept, 0.5 mg. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J0215?
The CMS HCPCS file marks J0215 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
Is J0215 still valid?
No. J0215 was terminated on December 31, 2025 and should not be used on new claims.