J0365 — Injection, aprotonin, 10,000 kiu
J0365 is a HCPCS Level II code for injection, aprotonin, 10,000 kiu. It belongs to the Drugs Administered Other Than Oral Method section. It was terminated on December 31, 2025 and is not valid on new claims.
This code has been terminated
CMS terminated J0365 on December 31, 2025. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
The CMS record for J0365
- Long descriptor
- Injection, aprotonin, 10,000 kiu
- Short descriptor
- Aprotonin, 10,000 kiu
- Added
- January 1, 2006
- Terminated
- December 31, 2025
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J0365
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J0365 is not quite right, the correct code is very often within a few positions of it.
- J0295Injection, ampicillin sodium/sulbactam sodium, per 1.5 gm
- J0300Injection, amobarbital, up to 125 mg
- J0330Injection, succinylcholine chloride, up to 20 mg
- J0348Injection, anidulafungin, 1 mg
- J0349Injection, rezafungin, 1 mg
- J0350Injection, anistreplase, per 30 unitsterminated
- J0360Injection, hydralazine hcl, up to 20 mg
- J0364Injection, apomorphine hydrochloride, 1 mg
- J0380Injection, metaraminol bitartrate, per 10 mgterminated
- J0390Injection, chloroquine hydrochloride, up to 250 mg
- J0391Injection, artesunate, 1 mg
- J0395Injection, arbutamine hcl, 1 mgterminated
- J0400Injection, aripiprazole, intramuscular, 0.25 mg
- J0401Injection, aripiprazole (abilify maintena), 1 mg
- J0402Injection, aripiprazole (abilify asimtufii), 1 mg
- J0456Injection, azithromycin, 500 mg
Questions about J0365
What is HCPCS code J0365?
J0365 is a HCPCS Level II code for injection, aprotonin, 10,000 kiu. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J0365?
The CMS HCPCS file marks J0365 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
Is J0365 still valid?
No. J0365 was terminated on December 31, 2025 and should not be used on new claims.