J0775 — Injection, collagenase, clostridium histolyticum, 0.01 mg
J0775 is a HCPCS Level II code for injection, collagenase, clostridium histolyticum, 0.01 mg. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusE
Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
Medically Unlikely Edits — units per day
The most units of J0775 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.
- practitioner
- 180 units MAI 3 — Date of Service Edit: Clinical · CMS Policy
- outpatient
- 180 units MAI 3 — Date of Service Edit: Clinical · CMS Policy
- DME supplier
- 0 — never payable MAI 3 — Date of Service Edit: Clinical · CMS Policy
The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute — no documentation overrides it. CMS MUE 2026Q3.
The CMS record for J0775
- Long descriptor
- Injection, collagenase, clostridium histolyticum, 0.01 mg
- Short descriptor
- Collagenase, clost hist inj
- Added
- January 1, 2011
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J0775
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J0775 is not quite right, the correct code is very often within a few positions of it.
- J0744Injection, ciprofloxacin for intravenous infusion, 200 mg
- J0745Injection, codeine phosphate, per 30 mg
- J0750Emtricitabine 200mg and tenofovir disoproxil fumarate 300mg, oral, fda approved prescription, only for use as hiv pre-exposure prophylaxis (not for use as treatment of hiv)
- J0751Emtricitabine 200mg and tenofovir alafenamide 25mg, oral, fda approved prescription, only for use as hiv pre-exposure prophylaxis (not for use as treatment of hiv)
- J0752Oral, lenacapavir, 300 mg, fda approved prescription, only for use as hiv pre-exposure prophylaxis (not for use as treatment for hiv)
- J0759Injection, clevidipine butyrate, 1 mg
- J0760Injection, colchicine, per 1 mgterminated
- J0770Injection, colistimethate sodium, up to 150 mg
- J0780Injection, prochlorperazine, up to 10 mg
- J0791Injection, crizanlizumab-tmca, 5 mg
- J0795Injection, corticorelin ovine triflutate, 1 microgramterminated
- J0799Fda approved prescription drug, only for use as hiv pre-exposure prophylaxis (not for use as treatment of hiv), not otherwise classified
- J0800Injection, corticotropin, up to 40 unitsterminated
- J0801Injection, corticotropin (acthar gel), up to 40 units
- J0802Injection, corticotropin (ani), up to 40 units
- J0833Injection, cosyntropin, not otherwise specified, 0.25 mgterminated
Questions about J0775
What is HCPCS code J0775?
J0775 is a HCPCS Level II code for injection, collagenase, clostridium histolyticum, 0.01 mg. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J0775?
The CMS HCPCS file marks J0775 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is J0775 paid under the physician fee schedule?
J0775 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).