J3291 — Injection, tranexamic acid in sodium chloride, 5 mg
J3291 is a HCPCS Level II code for injection, tranexamic acid in sodium chloride, 5 mg. It belongs to the Drugs Administered Other Than Oral Method section. Medicare does not pay it — see the coverage note below before you bill it.
Medicare coverage: Not payable by Medicare
Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusN
Non-covered service. Medicare does not cover it.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for J3291
- Long descriptor
- Injection, tranexamic acid in sodium chloride, 5 mg
- Short descriptor
- Tranexamic acid in sod chlor
- Added
- January 1, 2026
- BETOS
- O1E
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to J3291
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J3291 is not quite right, the correct code is very often within a few positions of it.
- J3250Injection, trimethobenzamide hcl, up to 200 mg
- J3260Injection, tobramycin sulfate, up to 80 mg
- J3262Injection, tocilizumab, 1 mg
- J3263Injection, toripalimab-tpzi, 1 mg
- J3265Injection, torsemide, 10 mg/ml
- J3280Injection, thiethylperazine maleate, up to 10 mgterminated
- J3285Injection, treprostinil, 1 mg
- J3290Injection, tranexamic acid, 5 mg
- J3299Injection, triamcinolone acetonide (xipere), 1 mg
- J3300Injection, triamcinolone acetonide, preservative free, 1 mg
- J3301Injection, triamcinolone acetonide, not otherwise specified, 10 mg
- J3302Injection, triamcinolone diacetate, per 5 mg
- J3303Injection, triamcinolone hexacetonide, per 5 mg
- J3304Injection, triamcinolone acetonide, preservative-free, extended-release, microsphere formulation, 1 mg
- J3305Injection, trimetrexate glucuronate, per 25 mgterminated
- J3310Injection, perphenazine, up to 5 mgterminated
Questions about J3291
What is HCPCS code J3291?
J3291 is a HCPCS Level II code for injection, tranexamic acid in sodium chloride, 5 mg. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J3291?
The CMS HCPCS file marks J3291 as "Not payable by Medicare". Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
How is J3291 paid under the physician fee schedule?
J3291 carries PFS status code N. Non-covered service. Medicare does not cover it.