J7210 — Injection, factor viii, (antihemophilic factor, recombinant), (afstyla), 1 i.u.
J7210 is a HCPCS Level II code for injection, factor viii, (antihemophilic factor, recombinant), (afstyla), 1 i.u.. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusE
Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
Medically Unlikely Edits — units per day
The most units of J7210 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.
- practitioner
- 22000 units MAI 1 — Line Edit · Clinical: CMS Workgroup
- outpatient
- 22000 units MAI 1 — Line Edit · Clinical: CMS Workgroup
The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute — no documentation overrides it. CMS MUE 2026Q3.
The CMS record for J7210
- Long descriptor
- Injection, factor viii, (antihemophilic factor, recombinant), (afstyla), 1 i.u.
- Short descriptor
- Inj, afstyla, 1 i.u.
- Added
- January 1, 2018
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J7210
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J7210 is not quite right, the correct code is very often within a few positions of it.
- J7201Injection, factor ix, fc fusion protein, (recombinant), alprolix, 1 i.u.
- J7202Injection, factor ix, albumin fusion protein, (recombinant), idelvion, 1 i.u.
- J7203Injection factor ix, (antihemophilic factor, recombinant), glycopegylated, (rebinyn), 1 iu
- J7204Injection, factor viii, antihemophilic factor (recombinant), (esperoct), glycopegylated-exei, per iu
- J7205Injection, factor viii fc fusion protein (recombinant), per iu
- J7207Injection, factor viii, (antihemophilic factor, recombinant), pegylated, 1 i.u.
- J7208Injection, factor viii, (antihemophilic factor, recombinant), pegylated-aucl, (jivi), 1 i.u.
- J7209Injection, factor viii, (antihemophilic factor, recombinant), (nuwiq), 1 i.u.
- J7211Injection, factor viii, (antihemophilic factor, recombinant), (kovaltry), 1 i.u.
- J7212Factor viia (antihemophilic factor, recombinant)-jncw (sevenfact), 1 microgram
- J7213Injection, coagulation factor ix (recombinant), ixinity, 1 i.u.
- J7214Injection, factor viii/von willebrand factor complex, recombinant (altuviiio), per factor viii i.u.
- J7294Segesterone acetate and ethinyl estradiol 0.15mg, 0.013mg per 24 hours; yearly vaginal system, each
- J7295Ethinyl estradiol and etonogestrel 0.015mg, 0.12mg per 24 hours; monthly vaginal ring, each
- J7296Levonorgestrel-releasing intrauterine contraceptive system, (kyleena), 19.5 mg
- J7297Levonorgestrel-releasing intrauterine contraceptive system (liletta), 52 mg
Questions about J7210
What is HCPCS code J7210?
J7210 is a HCPCS Level II code for injection, factor viii, (antihemophilic factor, recombinant), (afstyla), 1 i.u.. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J7210?
The CMS HCPCS file marks J7210 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is J7210 paid under the physician fee schedule?
J7210 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).