J7331 — Hyaluronan or derivative, synojoynt, for intra-articular injection, 1 mg
J7331 is a HCPCS Level II code for hyaluronan or derivative, synojoynt, for intra-articular injection, 1 mg. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusE
Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
Medically Unlikely Edits — units per day
The most units of J7331 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.
- practitioner
- 40 units MAI 3 — Date of Service Edit: Clinical · Prescribing Information
- outpatient
- 40 units MAI 3 — Date of Service Edit: Clinical · Prescribing Information
The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute — no documentation overrides it. CMS MUE 2026Q3.
The CMS record for J7331
- Long descriptor
- Hyaluronan or derivative, synojoynt, for intra-articular injection, 1 mg
- Short descriptor
- Synojoynt, inj., 1 mg
- Added
- October 1, 2019
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J7331
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J7331 is not quite right, the correct code is very often within a few positions of it.
- J7323Hyaluronan or derivative, euflexxa, for intra-articular injection, per dose
- J7324Hyaluronan or derivative, orthovisc, for intra-articular injection, per dose
- J7325Hyaluronan or derivative, synvisc or synvisc-one, for intra-articular injection, 1 mg
- J7326Hyaluronan or derivative, gel-one, for intra-articular injection, per dose
- J7327Hyaluronan or derivative, monovisc, for intra-articular injection, per dose
- J7328Hyaluronan or derivative, gelsyn-3, for intra-articular injection, 0.1 mg
- J7329Hyaluronan or derivative, trivisc, for intra-articular injection, 1 mg
- J7330Autologous cultured chondrocytes, implant
- J7332Hyaluronan or derivative, triluron, for intra-articular injection, 1 mg
- J7333Hyaluronan or derivative, visco-3, for intra-articular injection, per doseterminated
- J7335Capsaicin 8% patch, per 10 square centimetersterminated
- J7336Capsaicin 8% patch, per square centimeter
- J7340Carbidopa 5 mg/levodopa 20 mg enteral suspension, 100 ml
- J7342Instillation, ciprofloxacin otic suspension, 6 mg
- J7345Aminolevulinic acid hcl for topical administration, 10% gel, 10 mg
- J7351Injection, bimatoprost, intracameral implant, 1 microgram
Questions about J7331
What is HCPCS code J7331?
J7331 is a HCPCS Level II code for hyaluronan or derivative, synojoynt, for intra-articular injection, 1 mg. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J7331?
The CMS HCPCS file marks J7331 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is J7331 paid under the physician fee schedule?
J7331 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).