J7503 — Tacrolimus, extended release, (envarsus xr), oral, 0.25 mg
J7503 is a HCPCS Level II code for tacrolimus, extended release, (envarsus xr), oral, 0.25 mg. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusE
Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
Medically Unlikely Edits — units per day
The most units of J7503 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.
- practitioner
- 0 — never payable MAI 3 — Date of Service Edit: Clinical · Oral Medication; Not Payable
- outpatient
- 120 units MAI 3 — Date of Service Edit: Clinical · Prescribing Information
- DME supplier
- 3600 units MAI 3 — Date of Service Edit: Clinical · Prescribing Information
The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute — no documentation overrides it. CMS MUE 2026Q3.
The CMS record for J7503
- Long descriptor
- Tacrolimus, extended release, (envarsus xr), oral, 0.25 mg
- Short descriptor
- Tacrol envarsus ex rel oral
- Added
- January 1, 2016
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J7503
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J7503 is not quite right, the correct code is very often within a few positions of it.
- J7354Cantharidin for topical administration, 0.7%, single unit dose applicator (3.2 mg)
- J7355Injection, travoprost, intracameral implant, 1 microgram
- J7356Injection, foscarbidopa 0.25 mg/foslevodopa 5 mg
- J7401Mometasone furoate sinus implant, 10 microgramsterminated
- J7402Mometasone furoate sinus implant, (sinuva), 10 micrograms
- J7500Azathioprine, oral, 50 mg
- J7501Azathioprine, parenteral, 100 mg
- J7502Cyclosporine, oral, 100 mg
- J7504Lymphocyte immune globulin, antithymocyte globulin, equine, parenteral, 250 mg
- J7505Muromonab-cd3, parenteral, 5 mgterminated
- J7506Prednisone, oral, per 5 mgterminated
- J7507Tacrolimus, immediate release, oral, 1 mg
- J7508Tacrolimus, extended release, (astagraf xl), oral, 0.1 mg
- J7509Methylprednisolone oral, per 4 mg
- J7510Prednisolone oral, per 5 mg
- J7511Lymphocyte immune globulin, antithymocyte globulin, rabbit, parenteral, 25 mg
Questions about J7503
What is HCPCS code J7503?
J7503 is a HCPCS Level II code for tacrolimus, extended release, (envarsus xr), oral, 0.25 mg. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J7503?
The CMS HCPCS file marks J7503 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
How is J7503 paid under the physician fee schedule?
J7503 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).