Q4159 — Affinity, per square centimeter (add-on, list separately in addition to primary procedure)
Q4159 is a HCPCS Level II code for affinity, per square centimeter (add-on, list separately in addition to primary procedure). It belongs to the Temporary Codes section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusA
Active code. Paid separately under the physician fee schedule.
- Work RVU
- 0.00
- PE (non-facility)
- 3.81
- PE (facility)
- 3.81
- Malpractice RVU
- 0.00
Global period: ZZZ
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for Q4159
- Long descriptor
- Affinity, per square centimeter (add-on, list separately in addition to primary procedure)
- Short descriptor
- Affinity1 square cm
- Added
- January 1, 2015
- BETOS
- O1E
- Pricing indicator
- 11 — Physician fee schedule
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Price established using national RVUs.
Codes adjacent to Q4159
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If Q4159 is not quite right, the correct code is very often within a few positions of it.
- Q4151Amnioband or guardian, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4152Dermapure, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4153Dermavest and plurivest, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4154Biovance, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4155Neoxflo or clarixflo, 1 mg
- Q4156Neox 100 or clarix 100, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4157Revitalon, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4158Kerecis omega3, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4160Nushield, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4161Bio-connekt wound matrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4162Woundex flow, bioskin flow, 0.5 cc
- Q4163Woundex, bioskin, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4164Helicoll, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4165Keramatrix or kerasorb, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4166Cytal, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4167Truskin, per square centimeter (add-on, list separately in addition to primary procedure)
Questions about Q4159
What is HCPCS code Q4159?
Q4159 is a HCPCS Level II code for affinity, per square centimeter (add-on, list separately in addition to primary procedure). It sits in the Temporary Codes section.
Does Medicare cover Q4159?
The CMS HCPCS file marks Q4159 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is Q4159 paid under the physician fee schedule?
Q4159 carries PFS status code A. Active code. Paid separately under the physician fee schedule.