Q4253 — Zenith amniotic membrane, per square centimeter (add-on, list separately in addition to primary procedure)
Q4253 is a HCPCS Level II code for zenith amniotic membrane, per square centimeter (add-on, list separately in addition to primary procedure). It belongs to the Temporary Codes section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusA
Active code. Paid separately under the physician fee schedule.
- Work RVU
- 0.00
- PE (non-facility)
- 3.81
- PE (facility)
- 3.81
- Malpractice RVU
- 0.00
Global period: ZZZ
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The CMS record for Q4253
- Long descriptor
- Zenith amniotic membrane, per square centimeter (add-on, list separately in addition to primary procedure)
- Short descriptor
- Zenith amniotic membrane psc
- Added
- October 1, 2021
- BETOS
- O1E
- Pricing indicator
- 11 — Physician fee schedule
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Price established using national RVUs.
Codes adjacent to Q4253
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If Q4253 is not quite right, the correct code is very often within a few positions of it.
- Q4245Amniotext, per cc
- Q4246Coretext or protext, per cc
- Q4247Amniotext patch, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4248Dermacyte amniotic membrane allograft, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4249Amniply, for topical use only, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4250Amnioamp-mp, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4251Vim, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4252Vendaje, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4254Novafix dl, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4255Reguard, for topical use only, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4256Mlg-complete, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4257Relese, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4258Enverse, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4259Celera dual layer or celera dual membrane, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4260Signature apatch, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4261Tag, per square centimeter (add-on, list separately in addition to primary procedure)
Questions about Q4253
What is HCPCS code Q4253?
Q4253 is a HCPCS Level II code for zenith amniotic membrane, per square centimeter (add-on, list separately in addition to primary procedure). It sits in the Temporary Codes section.
Does Medicare cover Q4253?
The CMS HCPCS file marks Q4253 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is Q4253 paid under the physician fee schedule?
Q4253 carries PFS status code A. Active code. Paid separately under the physician fee schedule.