Q4280 — Xcell amnio matrix, per square centimeter (add-on, list separately in addition to primary procedure)
Q4280 is a HCPCS Level II code for xcell amnio matrix, per square centimeter (add-on, list separately in addition to primary procedure). It belongs to the Temporary Codes section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusA
Active code. Paid separately under the physician fee schedule.
- Work RVU
- 0.00
- PE (non-facility)
- 3.81
- PE (facility)
- 3.81
- Malpractice RVU
- 0.00
Global period: ZZZ
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The CMS record for Q4280
- Long descriptor
- Xcell amnio matrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Short descriptor
- Xcell amnio matrix per sq cm
- Added
- July 1, 2023
- BETOS
- O1E
- Pricing indicator
- 11 — Physician fee schedule
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Price established using national RVUs.
Codes adjacent to Q4280
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If Q4280 is not quite right, the correct code is very often within a few positions of it.
- Q4272Esano a, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4273Esano aaa, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4274Esano ac, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4275Esano aca, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4276Orion, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4277Woundplus membrane or e-graft, per square centimeterterminated
- Q4278Epieffect, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4279Vendaje ac, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4281Barrera sl or barrera dl, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4282Cygnus dual, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4283Biovance tri-layer or biovance 3l, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4284Dermabind sl, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4285Nudyn dl or nudyn dl mesh, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4286Nudyn sl or nudyn slw, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4287Dermabind dl, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4288Dermabind ch, per square centimeter (add-on, list separately in addition to primary procedure)
Questions about Q4280
What is HCPCS code Q4280?
Q4280 is a HCPCS Level II code for xcell amnio matrix, per square centimeter (add-on, list separately in addition to primary procedure). It sits in the Temporary Codes section.
Does Medicare cover Q4280?
The CMS HCPCS file marks Q4280 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is Q4280 paid under the physician fee schedule?
Q4280 carries PFS status code A. Active code. Paid separately under the physician fee schedule.