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Q5148

Q5148Injection, filgrastim-txid (nypozi), biosimilar, 1 microgram

HCPCSActiveBETOS O1E

Q5148 is a HCPCS Level II code for injection, filgrastim-txid (nypozi), biosimilar, 1 microgram. It belongs to the Temporary Codes section. Whether Medicare pays it depends on the coverage rule below.

Medicare coverage: Special coverage instructions apply

There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.

From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.

Physician fee schedule statusE

Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).

Global period: XXX

Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.

Medically Unlikely Edits — units per day

The most units of Q5148 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.

practitioner
1500 units
MAI 3 — Date of Service Edit: Clinical · Prescribing Information
outpatient
1500 units
MAI 3 — Date of Service Edit: Clinical · Prescribing Information
DME supplier
1500 units
MAI 3 — Date of Service Edit: Clinical · Prescribing Information

The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute — no documentation overrides it. CMS MUE 2026Q3.

The CMS record for Q5148

Long descriptor
Injection, filgrastim-txid (nypozi), biosimilar, 1 microgram

The official wording. This is what the code means.

Short descriptor
Inj, nyposi 1 mcg

CMS's 28-character form, which is what shows up on a remittance advice.

Added
April 1, 2025

When CMS introduced the code.

BETOS
O1E

Berenson-Eggers Type of Service — CMS's own analytic grouping.

Pricing indicator
51 — Other

Drugs.

Codes adjacent to Q5148

HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If Q5148 is not quite right, the correct code is very often within a few positions of it.

  • Q5140Injection, adalimumab-fkjp, biosimilar, 1 mg
  • Q5141Injection, adalimumab-aaty, biosimilar, 1 mg
  • Q5142Injection, adalimumab-ryvk biosimilar, 1 mg
  • Q5143Injection, adalimumab-adbm, biosimilar, 1 mg
  • Q5144Injection, adalimumab-aacf (idacio), biosimilar, 1 mg
  • Q5145Injection, adalimumab-afzb (abrilada), biosimilar, 1 mg
  • Q5146Injection, trastuzumab-strf (hercessi), biosimilar, 10 mg
  • Q5147Injection, aflibercept-ayyh (pavblu), biosimilar, 1 mg
  • Q5149Injection, aflibercept-abzv (enzeevu), biosimilar, 1 mg
  • Q5150Injection, aflibercept-mrbb (ahzantive), biosimilar, 1 mg
  • Q5151Injection, eculizumab-aagh (epysqli), biosimilar, 2 mg
  • Q5152Injection, eculizumab-aeeb (bkemv), biosimilar, 2 mg
  • Q5153Injection, aflibercept-yszy (opuviz), biosimilar, 1 mg
  • Q5154Injection, omalizumab-igec (omlyclo), biosimilar, 5 mg
  • Q5155Injection, aflibercept-jbvf (yesafili), biosimilar, 1 mg
  • Q5156Injection, tocilizumab-anoh (avtozma), biosimilar, 1 mg

Questions about Q5148

What is HCPCS code Q5148?

Q5148 is a HCPCS Level II code for injection, filgrastim-txid (nypozi), biosimilar, 1 microgram. It sits in the Temporary Codes section.

Does Medicare cover Q5148?

The CMS HCPCS file marks Q5148 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.

How is Q5148 paid under the physician fee schedule?

Q5148 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).

HCPCS Level II2026Q3-Jul· effective July 1, 2026