S0191 — Misoprostol, oral, 200 mcg
S0191 is a HCPCS Level II code for misoprostol, oral, 200 mcg. It belongs to the Temporary National Codes (Non-Medicare) section. Medicare does not pay it — see the coverage note below before you bill it.
Medicare coverage: Not payable by Medicare
Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusI
Not valid for Medicare purposes. Medicare uses another code.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for S0191
- Long descriptor
- Misoprostol, oral, 200 mcg
- Short descriptor
- Misoprostol, oral, 200 mcg
- Added
- January 1, 2001
- BETOS
- Z2
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to S0191
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If S0191 is not quite right, the correct code is very often within a few positions of it.
- S0177Levamisole hydrochloride, oral, 50 mg
- S0178Lomustine, oral, 10 mg
- S0179Megestrol acetate, oral, 20 mg
- S0182Procarbazine hydrochloride, oral, 50 mg
- S0183Prochlorperazine maleate, oral, 5 mg (for circumstances falling under the medicare statute, use q0164)
- S0187Tamoxifen citrate, oral, 10 mg
- S0189Testosterone pellet, 75 mgterminated
- S0190Mifepristone, oral, 200 mg
- S0194Dialysis/stress vitamin supplement, oral, 100 capsules
- S0195Pneumococcal conjugate vaccine, polyvalent, intramuscular, for children from five years to nine years of age who have not previously received the vaccineterminated
- S0197Prenatal vitamins, 30-day supply
- S0199Medically induced abortion by oral ingestion of medication including all associated services and supplies (e.g., patient counseling, office visits, confirmation of pregnancy by hcg, ultrasound to confirm duration of pregnancy, ultrasound to confirm completion of abortion) except drugs
- S0201Partial hospitalization services, less than 24 hours, per diem
- S0207Paramedic intercept, non-hospital-based als service (non-voluntary), non-transport
- S0208Paramedic intercept, hospital-based als service (non-voluntary), non-transport
- S0209Wheelchair van, mileage, per mile
Questions about S0191
What is HCPCS code S0191?
S0191 is a HCPCS Level II code for misoprostol, oral, 200 mcg. It sits in the Temporary National Codes (Non-Medicare) section.
Does Medicare cover S0191?
The CMS HCPCS file marks S0191 as "Not payable by Medicare". Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
How is S0191 paid under the physician fee schedule?
S0191 carries PFS status code I. Not valid for Medicare purposes. Medicare uses another code.