S5001 — Prescription drug, brand name
S5001 is a HCPCS Level II code for prescription drug, brand name. It belongs to the Temporary National Codes (Non-Medicare) section. Medicare does not pay it — see the coverage note below before you bill it.
Medicare coverage: Not payable by Medicare
Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusI
Not valid for Medicare purposes. Medicare uses another code.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for S5001
- Long descriptor
- Prescription drug, brand name
- Short descriptor
- Prescription drug,brand name
- Added
- January 1, 2001
- BETOS
- Z2
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to S5001
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If S5001 is not quite right, the correct code is very often within a few positions of it.
- S4981Insertion of levonorgestrel-releasing intrauterine system
- S4988Penile contracture device, manual, greater than 3 lbs traction forceterminated
- S4989Contraceptive intrauterine device (e.g., progestacert iud), including implants and supplies
- S4990Nicotine patches, legend
- S4991Nicotine patches, non-legend
- S4993Contraceptive pills for birth control
- S4995Smoking cessation gum
- S5000Prescription drug, generic
- S50105% dextrose and 0.45% normal saline, 1000 ml
- S50115% dextrose in lactated ringer's, 1000 mlterminated
- S50125% dextrose with potassium chloride, 1000 ml
- S50135% dextrose/0.45% normal saline with potassium chloride and magnesium sulfate, 1000 ml
- S50145% dextrose/0.45% normal saline with potassium chloride and magnesium sulfate, 1500 ml
- S5035Home infusion therapy, routine service of infusion device (e.g., pump maintenance)
- S5036Home infusion therapy, repair of infusion device (e.g., pump repair)
- S5100Day care services, adult; per 15 minutes
Questions about S5001
What is HCPCS code S5001?
S5001 is a HCPCS Level II code for prescription drug, brand name. It sits in the Temporary National Codes (Non-Medicare) section.
Does Medicare cover S5001?
The CMS HCPCS file marks S5001 as "Not payable by Medicare". Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
How is S5001 paid under the physician fee schedule?
S5001 carries PFS status code I. Not valid for Medicare purposes. Medicare uses another code.