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ICD-10-CM tabular list

D37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes

ICD-10-CM codes D37-D48 cover neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes, within neoplasms. The block holds 140 codes across 12 categories, of which 115 are billable and 25 are header codes that cannot be submitted on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • neoplasms of unspecified behavior (D49.-)

Notes

Additional guidance from the ICD-10-CM tabular list.

  • Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made.

Risk adjustment in D37-D48

0 codes in this block map to a CMS-HCC, which means the diagnosis carries a risk-adjustment payment when it is documented and coded. Under-coding here is money left on the table; over-coding here is what audits are for.

  • HCC 23 Prostate, Breast, and Other Cancers and Tumors
  • HCC 19 Myelodysplastic Syndromes, Multiple Myeloma, and Other Cancers
  • HCC 21 Lymphoma and Other Cancers
  • HCC 17 Cancer Metastatic to Lung, Liver, Brain, and Other Organs; Acute Myeloid Leukemia Except Promyelocytic

What else to watch in D37-D48

  • 14 codes are laterality-specific. They come in left and right pairs, and the pair is mutually exclusive on a single site: coding both without a bilateral code is a contradiction a scrubber should catch before the payer does.
  • 115 codes are named in Medicare coverage policies. An LCD or NCD lists them as supporting medical necessity, or explicitly as not supporting it. Which applies depends on the MAC for your state.

Categories in D37-D48

ICD-10-CMFY2026-Apr· effective April 1, 2026