MCMCB Pro
D46

D46Myelodysplastic syndromes

Non-billable headerICD-10-CM

D46 is a non-billable header ICD-10-CM code for myelodysplastic syndromes. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes2 — not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

  • drug-induced aplastic anemia (D61.1)

Use additional code

Add a secondary code to capture the detail described below.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Other codes that can never be billed with D46

These codes carry an Excludes1 note pointing at D46. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading D46 alone.

  • D72Other disorders of white blood cells
  • C94Other leukemias of specified cell type
  • D64Other anemias
  • C92.0Acute myeloblastic leukemia

Risk adjustment

D46 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead D46

9 child codes. Green means billable.

Questions about D46

Is D46 a billable ICD-10-CM code?
No. D46 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does D46 sit in the tabular list?
Neoplasms (C00-D49), in the block Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.