MCMCB Pro
E16

E16Other disorders of pancreatic internal secretion

Non-billable headerICD-10-CM

E16 is a non-billable header ICD-10-CM code for other disorders of pancreatic internal secretion. It cannot be billed on its own: choose one of the more specific child codes below.

Other codes that can never be billed with E16

These codes carry an Excludes1 note pointing at E16. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E16 alone.

  • R73.0Abnormal glucose
  • R79Other abnormal findings of blood chemistry
  • E22.0Acromegaly and pituitary gigantism
  • E74Other disorders of carbohydrate metabolism
  • E89.1Postprocedural hypoinsulinemia
  • K29Gastritis and duodenitis

Risk adjustment

E16 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead E16

8 child codes. Green means billable.

Questions about E16

Is E16 a billable ICD-10-CM code?
No. E16 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does E16 sit in the tabular list?
Endocrine, nutritional and metabolic diseases (E00-E89), in the block Other disorders of glucose regulation and pancreatic internal secretion (E15-E16).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.