Is E88.3 a billable ICD-10-CM code?

Yes. E88.3 is a billable, specific ICD-10-CM code and is valid for submission on a claim.

Where does E88.3 sit in the tabular list?

Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).

E88.3

E88.3 — Tumor lysis syndrome

Billable / specific codeICD-10-CM

E88.3 is a billable, specific ICD-10-CM code for tumor lysis syndrome. It is valid for submission on a claim.

Use additional code

Add a secondary code to capture the detail described below.

code for adverse effect, if applicable, to identify drug (T45.1X5)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Tumor lysis syndrome (spontaneous)
Tumor lysis syndrome following antineoplastic drug chemotherapy

Risk adjustment

E88.3 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

E88.3 is named in 3 Medicare coverage policies — 3 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

A56421Billing and Coding: CT of the Abdomen and Pelvis
A56717Billing and Coding: Respiratory Therapy (Respiratory Care)
A57224Billing and Coding: Respiratory Care

How E88.3 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E88.3.

Tumor lysis syndrome NEC(following antineoplastic chemotherapy) (spontaneous)
Syndrome›tumor lysis NEC(following antineoplastic chemotherapy) (spontaneous)

Related codes at this level

Codes that share E88. If E88.3 is not quite right, the correct code is usually one of these.

Questions about E88.3

Is E88.3 a billable ICD-10-CM code?: Yes. E88.3 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does E88.3 sit in the tabular list?: Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).