Is E88 a billable ICD-10-CM code?

No. E88 is a non-billable header code. Code to a higher level of specificity using one of its child codes.

Where does E88 sit in the tabular list?

Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).

What cannot be coded together with E88?

E88 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.

E88

E88 — Other and unspecified metabolic disorders

Non-billable headerICD-10-CM

E88 is a non-billable header ICD-10-CM code for other and unspecified metabolic disorders. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

histiocytosis X (chronic) (C96.6)

Use additional code

Add a secondary code to capture the detail described below.

codes for associated conditions

Other codes that can never be billed with E88

These codes carry an Excludes1 note pointing at E88. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E88 alone.

P59Neonatal jaundice from other and unspecified causes
R64Cachexia
R73.0Abnormal glucose
R77Other abnormalities of plasma proteins
G71.3Mitochondrial myopathy, not elsewhere classified

Risk adjustment

E88 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead E88

8 child codes. Green means billable.

Questions about E88

Is E88 a billable ICD-10-CM code?: No. E88 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does E88 sit in the tabular list?: Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
What cannot be coded together with E88?: E88 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.