J0288 — Injection, amphotericin b cholesteryl sulfate complex, 10 mg
J0288 is a HCPCS Level II code for injection, amphotericin b cholesteryl sulfate complex, 10 mg. It belongs to the Drugs Administered Other Than Oral Method section. It was terminated on December 31, 2025 and is not valid on new claims.
This code has been terminated
CMS terminated J0288 on December 31, 2025. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
The CMS record for J0288
- Long descriptor
- Injection, amphotericin b cholesteryl sulfate complex, 10 mg
- Short descriptor
- Ampho b cholesteryl sulfate
- Added
- January 1, 2003
- Terminated
- December 31, 2025
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J0288
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J0288 is not quite right, the correct code is very often within a few positions of it.
- J0275Alprostadil urethral suppository (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered)
- J0278Injection, amikacin sulfate, 100 mg
- J0280Injection, aminophyllin, up to 250 mg
- J0281Injection, aminocaproic acid, 1 gram
- J0282Injection, amiodarone hydrochloride, 30 mg
- J0283Injection, amiodarone hydrochloride (nexterone), 30 mg
- J0285Injection, amphotericin b, 50 mg
- J0287Injection, amphotericin b lipid complex, 10 mg
- J0289Injection, amphotericin b liposome, 10 mg
- J0290Injection, ampicillin sodium, 500 mg
- J0291Injection, plazomicin, 5 mg
- J0295Injection, ampicillin sodium/sulbactam sodium, per 1.5 gm
- J0300Injection, amobarbital, up to 125 mg
- J0330Injection, succinylcholine chloride, up to 20 mg
- J0348Injection, anidulafungin, 1 mg
- J0349Injection, rezafungin, 1 mg
Questions about J0288
What is HCPCS code J0288?
J0288 is a HCPCS Level II code for injection, amphotericin b cholesteryl sulfate complex, 10 mg. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J0288?
The CMS HCPCS file marks J0288 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
Is J0288 still valid?
No. J0288 was terminated on December 31, 2025 and should not be used on new claims.