J0528 — Injection, fosfomycin disodium, 20 mg
J0528 is a HCPCS Level II code for injection, fosfomycin disodium, 20 mg. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusE
Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).
Global period: XXX
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The CMS record for J0528
- Long descriptor
- Injection, fosfomycin disodium, 20 mg
- Short descriptor
- Inj fosfomycin disodium 20mg
- Added
- July 1, 2026
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J0528
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J0528 is not quite right, the correct code is very often within a few positions of it.
- J0485Injection, belatacept, 1 mg
- J0490Injection, belimumab, 10 mg
- J0491Injection, anifrolumab-fnia, 1 mg
- J0500Injection, dicyclomine hcl, up to 20 mg
- J0515Injection, benztropine mesylate, per 1 mg
- J0517Injection, benralizumab, 1 mg
- J0520Injection, bethanechol chloride, myotonachol or urecholine, up to 5 mg
- J0525Injection, cefotetan disodium, 10 mg
- J0558Injection, penicillin g benzathine and penicillin g procaine, 100,000 units
- J0561Injection, penicillin g benzathine, 100,000 units
- J0565Injection, bezlotoxumab, 10 mg
- J0567Injection, cerliponase alfa, 1 mg
- J0570Buprenorphine implant, 74.2 mg
- J0571Buprenorphine, oral, 1 mg
- J0572Buprenorphine/naloxone, oral, less than or equal to 3 mg buprenorphine
- J0573Buprenorphine/naloxone, oral, greater than 3 mg, but less than or equal to 6 mg buprenorphine
Questions about J0528
What is HCPCS code J0528?
J0528 is a HCPCS Level II code for injection, fosfomycin disodium, 20 mg. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J0528?
The CMS HCPCS file marks J0528 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is J0528 paid under the physician fee schedule?
J0528 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).