J0573 — Buprenorphine/naloxone, oral, greater than 3 mg, but less than or equal to 6 mg buprenorphine
J0573 is a HCPCS Level II code for buprenorphine/naloxone, oral, greater than 3 mg, but less than or equal to 6 mg buprenorphine. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusE
Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
Medically Unlikely Edits — units per day
The most units of J0573 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.
- practitioner
- 0 — never payable MAI 3 — Date of Service Edit: Clinical · Oral Medication; Not Payable
- outpatient
- 0 — never payable MAI 3 — Date of Service Edit: Clinical · Oral Medication; Not Payable
- DME supplier
- 0 — never payable MAI 3 — Date of Service Edit: Clinical · CMS Policy
The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute — no documentation overrides it. CMS MUE 2026Q3.
The CMS record for J0573
- Long descriptor
- Buprenorphine/naloxone, oral, greater than 3 mg, but less than or equal to 6 mg buprenorphine
- Short descriptor
- Bupren/nal 3.1 to 6mg bupren
- Added
- January 1, 2015
- BETOS
- O1E
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to J0573
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J0573 is not quite right, the correct code is very often within a few positions of it.
- J0528Injection, fosfomycin disodium, 20 mg
- J0558Injection, penicillin g benzathine and penicillin g procaine, 100,000 units
- J0561Injection, penicillin g benzathine, 100,000 units
- J0565Injection, bezlotoxumab, 10 mg
- J0567Injection, cerliponase alfa, 1 mg
- J0570Buprenorphine implant, 74.2 mg
- J0571Buprenorphine, oral, 1 mg
- J0572Buprenorphine/naloxone, oral, less than or equal to 3 mg buprenorphine
- J0574Buprenorphine/naloxone, oral, greater than 6 mg, but less than or equal to 10 mg buprenorphine
- J0575Buprenorphine/naloxone, oral, greater than 10 mg buprenorphine
- J0576Injection, buprenorphine extended-release (brixadi), 1 mgterminated
- J0577Injection, buprenorphine extended-release (brixadi), less than or equal to 7 days of therapy
- J0578Injection, buprenorphine extended release (brixadi), greater than 7 days and up to 28 days of therapy
- J0582Injection, bivalirudin (endo), not therapeutically equivalent to j0583, 1 mg
- J0583Injection, bivalirudin, 1 mg
- J0584Injection, burosumab-twza 1 mg
Questions about J0573
What is HCPCS code J0573?
J0573 is a HCPCS Level II code for buprenorphine/naloxone, oral, greater than 3 mg, but less than or equal to 6 mg buprenorphine. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J0573?
The CMS HCPCS file marks J0573 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
How is J0573 paid under the physician fee schedule?
J0573 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).