S3620 — Newborn metabolic screening panel, includes test kit, postage and the laboratory tests specified by the state for inclusion in this panel (e.g., galactose; hemoglobin, electrophoresis; hydroxyprogesterone, 17-d; phenylalanine (pku); and thyroxine, total)
S3620 is a HCPCS Level II code for newborn metabolic screening panel, includes test kit, postage and the laboratory tests specified by the state for inclusion in this panel (e.g., galactose; hemoglobin, electrophoresis; hydroxyprogesterone, 17-d; phenylalanine (pku); and thyroxine, total). It belongs to the Temporary National Codes (Non-Medicare) section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusI
Not valid for Medicare purposes. Medicare uses another code.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for S3620
- Long descriptor
- Newborn metabolic screening panel, includes test kit, postage and the laboratory tests specified by the state for inclusion in this panel (e.g., galactose; hemoglobin, electrophoresis; hydroxyprogesterone, 17-d; phenylalanine (pku); and thyroxine, total)
- Short descriptor
- Newborn metabolic screening
- Added
- January 1, 2001
- BETOS
- Z2
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to S3620
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If S3620 is not quite right, the correct code is very often within a few positions of it.
- S2405Repair of sacrococcygeal teratoma in the fetus, procedure performed in utero
- S2409Repair, congenital malformation of fetus, procedure performed in utero, not otherwise classified
- S2411Fetoscopic laser therapy for treatment of twin-to-twin transfusion syndrome
- S2900Surgical techniques requiring use of robotic surgical system (list separately in addition to code for primary procedure)
- S3000Diabetic indicator; retinal eye exam, dilated, bilateral
- S3005Performance measurement, evaluation of patient self assessment, depression
- S3600Stat laboratory request (situations other than s3601)
- S3601Emergency stat laboratory charge for patient who is homebound or residing in a nursing facility
- S3630Eosinophil count, blood, direct
- S3645Hiv-1 antibody testing of oral mucosal transudate
- S3650Saliva test, hormone level; during menopause
- S3652Saliva test, hormone level; to assess preterm labor risk
- S3655Antisperm antibodies test (immunobead)
- S3708Gastrointestinal fat absorption study
- S3721Prostate cancer antigen 3 (pca3) testingterminated
- S3722Dose optimization by area under the curve (auc) analysis, for infusional 5-fluorouracil
Questions about S3620
What is HCPCS code S3620?
S3620 is a HCPCS Level II code for newborn metabolic screening panel, includes test kit, postage and the laboratory tests specified by the state for inclusion in this panel (e.g., galactose; hemoglobin, electrophoresis; hydroxyprogesterone, 17-d; phenylalanine (pku); and thyroxine, total). It sits in the Temporary National Codes (Non-Medicare) section.
Does Medicare cover S3620?
The CMS HCPCS file marks S3620 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
How is S3620 paid under the physician fee schedule?
S3620 carries PFS status code I. Not valid for Medicare purposes. Medicare uses another code.