S0028 — Injection, famotidine, 20 mg
S0028 is a HCPCS Level II code for injection, famotidine, 20 mg. It belongs to the Temporary National Codes (Non-Medicare) section. It was terminated on March 31, 2025 and is not valid on new claims.
This code has been terminated
CMS terminated S0028 on March 31, 2025. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Not payable by Medicare
Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
The CMS record for S0028
- Long descriptor
- Injection, famotidine, 20 mg
- Short descriptor
- Injection, famotidine, 20 mg
- Added
- January 1, 2000
- Terminated
- March 31, 2025
- BETOS
- Z2
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to S0028
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If S0028 is not quite right, the correct code is very often within a few positions of it.
- R0076Transportation of portable ekg to facility or location, per patient
- S0012Butorphanol tartrate, nasal spray, 25 mg
- S0013Esketamine, nasal spray, 1 mgterminated
- S0014Tacrine hydrochloride, 10 mg
- S0017Injection, aminocaproic acid, 5 gramsterminated
- S0020Injection, bupivicaine hydrochloride, 30 mlterminated
- S0021Injection, cefoperazone sodium, 1 gram
- S0023Injection, cimetidine hydrochloride, 300 mg
- S0030Injection, metronidazole, 500 mgterminated
- S0032Injection, nafcillin sodium, 2 gramsterminated
- S0034Injection, ofloxacin, 400 mg
- S0039Injection, sulfamethoxazole and trimethoprim, 10 mlterminated
- S0040Injection, ticarcillin disodium and clavulanate potassium, 3.1 grams
- S0073Injection, aztreonam, 500 mgterminated
- S0074Injection, cefotetan disodium, 500 mgterminated
- S0077Injection, clindamycin phosphate, 300 mgterminated
Questions about S0028
What is HCPCS code S0028?
S0028 is a HCPCS Level II code for injection, famotidine, 20 mg. It sits in the Temporary National Codes (Non-Medicare) section.
Does Medicare cover S0028?
The CMS HCPCS file marks S0028 as "Not payable by Medicare". Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
Is S0028 still valid?
No. S0028 was terminated on March 31, 2025 and should not be used on new claims.