S0074 — Injection, cefotetan disodium, 500 mg
S0074 is a HCPCS Level II code for injection, cefotetan disodium, 500 mg. It belongs to the Temporary National Codes (Non-Medicare) section. It was terminated on September 30, 2025 and is not valid on new claims.
This code has been terminated
CMS terminated S0074 on September 30, 2025. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Not payable by Medicare
Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
The CMS record for S0074
- Long descriptor
- Injection, cefotetan disodium, 500 mg
- Short descriptor
- Injection, cefotetan disodiu
- Added
- January 1, 2000
- Terminated
- September 30, 2025
- BETOS
- Z2
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to S0074
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If S0074 is not quite right, the correct code is very often within a few positions of it.
- S0023Injection, cimetidine hydrochloride, 300 mg
- S0028Injection, famotidine, 20 mgterminated
- S0030Injection, metronidazole, 500 mgterminated
- S0032Injection, nafcillin sodium, 2 gramsterminated
- S0034Injection, ofloxacin, 400 mg
- S0039Injection, sulfamethoxazole and trimethoprim, 10 mlterminated
- S0040Injection, ticarcillin disodium and clavulanate potassium, 3.1 grams
- S0073Injection, aztreonam, 500 mgterminated
- S0077Injection, clindamycin phosphate, 300 mgterminated
- S0078Injection, fosphenytoin sodium, 750 mg
- S0080Injection, pentamidine isethionate, 300 mgterminated
- S0081Injection, piperacillin sodium, 500 mg
- S0088Imatinib, 100 mg
- S0090Sildenafil citrate, 25 mg
- S0091Granisetron hydrochloride, 1 mg (for circumstances falling under the medicare statute, use q0166)
- S0092Injection, hydromorphone hydrochloride, 250 mg (loading dose for infusion pump)
Questions about S0074
What is HCPCS code S0074?
S0074 is a HCPCS Level II code for injection, cefotetan disodium, 500 mg. It sits in the Temporary National Codes (Non-Medicare) section.
Does Medicare cover S0074?
The CMS HCPCS file marks S0074 as "Not payable by Medicare". Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
Is S0074 still valid?
No. S0074 was terminated on September 30, 2025 and should not be used on new claims.